Vertex Pharmaceuticals Inc. (VRTX) stock price, quote and key numbers

Updated 28 September 2026, 09:52 ET

Vertex Pharmaceuticals Inc. (VRTX) closed at $526.19 on 25 September 2026, up 0.7%. That leaves it up 3.5% over a week, down 3.9% over a month and up 39.7% over a year. That is 81% of the way up its 52 week range of $377.02 to $560.25. The median analyst price target of $570 sits 8.3% above the close.

The price

Last close$526.19
Day+0.73%
1 week+3.51%
1 month-3.86%
3 months+7.09%
6 months+15.97%
Year to date+16.06%
1 year+39.71%
52 week high$560.25
52 week low$377.02
Volume756,207
Average volume, 3 months1,270,610
Market cap$132.4B

Changes compare dividend and split adjusted closes over trading sessions, so the one year figure is the last close against the close 252 sessions earlier. The 52 week range uses the daily highs and lows of the same window. Read the guide: How to read a stock quote.

The live price, the day's chart and the pre market and after hours prints are in the app: open VRTX in Just Stock Quotes.

Trend and range

VRTX trades above both its 50 day average of $514.31 and its 200 day average of $471.85, the shape of an uptrend. The 50 day average sits above the 200 day average. Its beta against the S&P 500 over the last year is 0.54, a stock that moves less than the market. It is 6.1% below its 52 week high and 39.6% above its 52 week low.

50 day average$514.31
200 day average$471.85
Above 50 dayYes
Above 200 dayYes
Beta, 1 year0.54
Range position81%

Moving averages smooth the closes of the last 50 and 200 sessions; being above or below them describes the trend, it does not predict it. Beta is how much the stock moved for each move in the S&P 500 over the year. Read the guide: Moving averages, the 52 week range and beta.

What analysts say

In the last 90 days 10 firms recorded 11 actions on VRTX: 9 kept a view and 2 new initiations. Price targets: 10 raised. The most recent targets from 11 firms run from $350 to $665, with a median of $570, 8.3% above the last close.

Actions, 90 days11
Firms10
Median target$570
Median vs close+8.33%
DateFirmActionPrice target
11 Sep 2026JP MorganReinstates Overweight$515.00 to $560.00
2 Sep 2026Morgan StanleyReinstates Overweight$665.00
5 Aug 2026Truist SecuritiesMaintains Buy$560.00 to $565.00
5 Aug 2026BarclaysMaintains Overweight$615.00 to $617.00
4 Aug 2026TD CowenMaintains Buy$525.00 to $550.00
4 Aug 2026Cantor FitzgeraldMaintains Overweight$590.00 to $595.00

A target is one firm's guess at the price a year out, and the average runs optimistic. The useful reading is the mood: high targets and a wall of buys mean high expectations. Read the guide: What analyst ratings and price targets tell you.

Earnings

The next report is on the calendar for 2 November 2026 for Q3 2026, with earnings per share expected at -$0.12. The last report, on 3 August 2026 for Q2 2026, showed EPS of $4.73 against $4.63 expected, a beat of 2.2%, on revenue of $3.3 billion. Vertex Pharmaceuticals Inc. beat the EPS estimate in 6 of its last 8 reported quarters.

Set a percent move alert before the report and the app pings you when the stock reacts, even after hours: open VRTX in Just Stock Quotes.

The numbers

Over the trailing twelve months Vertex Pharmaceuticals Inc. shows revenue growth of 10.23%, a gross margin of 86.00%, an operating margin of 37.95% and a return on equity of 23.54%.

MeasureValuePercentile
Revenue growth, TTM10.2%62nd
Net income growth, TTM21.1%58th
Gross margin86.0%94th
Operating margin38.0%93rd
Free cash flow margin30.2%91st
Return on equity23.5%89th
Return on assets17.1%95th
Debt to equity0.0132nd
Current ratio3.1980th
Effective tax rate16.5%59th

The percentile ranks the company against every US company the data covers; a high percentile means most companies score lower.

Margins say how much of each dollar of sales becomes profit, returns say how hard the balance sheet works, and debt to equity says how much of it is borrowed. The valuation ratios, price to earnings and the rest, are in the app on the stock page. Read the guide: The valuation ratios on a stock page.

About Vertex Pharmaceuticals Inc.

Exchange
Nasdaq
Sector
Health Care
Industry
Pharmaceutical Products
Headquarters
Boston, Massachusetts
Chief executive
Reshma Kewalramani
Employees
4,800
Website
vrtx.com

Vertex Pharmaceuticals Incorporated engages in developing and commercializing therapies for treating cystic fibrosis. The company markets SYMDEKO/SYMKEVI, ORKAMBI, and KALYDECO to treat patients with CF 6 years of age or older who have at least one F508del mutation. Its pipeline includes VX-864 for the treatment of AAT deficiency, which is in Phase 2 clinical trial.

In the same sector

Other Health Care names in the S&P 500, by market cap:

LLY Eli Lilly & Co.JNJ Johnson & JohnsonABBV AbbVie Inc.MRK Merck & Co. Inc.UNH UnitedHealth Group Inc.TMO Thermo Fisher Scientific Inc.AMGN Amgen Inc.GILD Gilead Sciences, Inc.

Learn

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